The Biden administration’s newly released National Blueprint for Transportation Decarbonization represents an historic mission alignment among federal agencies to meet an economy-wide goal of net-zero greenhouse gas emissions (GHG) by 2050. The U.S. Departments of Energy, Transportation, Housing and Urban Development, along with the Environmental Protection Agency, have developed this joint strategy to guide the decarbonization of the transportation sector—the largest GHG contributor, currently generating roughly one-third of U.S. emissions.